Celebrex is a modern non-steroidal anti-inflammation medication with a complex of actions – it removes painful sensations, reduces body temperature in fevers, blocks inflammatory processes. Functionality is due to the presence of the active component of Celecoxib. What is Celebrex? Preparation does not affect the processes of the gastrointestinal tract and is effective for the treatment of symptoms of osteoarthritis, rheumatism, ankylosing spondylitis. It is shown to be used for online pain relief of different etiology – muscular, postoperative, articular and others. Remedy is well established itself with menstrual pain.
What does Celebrex do?
It is anti-inflammatory drug of non-steroidal origin, which has a pronounced antipyretic effect. The mechanism of development of therapeutic action is associated with the blocking of prostaglandins – the main group of biologically active substances taking direct part in inflammation. The maximum concentration of Celebrex for pain after oral administration comes after 3 hours. Further, the preparation completely binds to plasma proteins and is evenly distributed throughout the body. The ability of medicament to penetrate through the natural protective barriers of the body is noted. Neutralization of pills occurs in the liver with the formation of inactive decay products. Removal of the drug occurs naturally. The use of active ingredient together with fatty foods leads to an increase in the time to reach the maximum concentration of the drug in the blood. It is quickly and completely absorbed when taken on an empty stomach. The metabolism of the anti-inflammatory tablets occurs in the liver, and the products of metabolism are excreted with feces and urine. This is a positive moment for people suffering from kidney pathology. If Сelebrex does not suit you according to the indications, the doctor will prescribe the appropriate analgesic medication for you as Indometacin or Aleve drug.
Composition and form of release
People get Celebrex online available in capsules containing one hundred or two hundred milligrams of the active substance (Celecoxib). In addition to the active substance, the capsule contains additional constituents.
In what doses and how many days to use Celebrex?
Recommended Celebrex dosage for elimination:
-symptoms of osteoarthritis: 200 mg of drug per day, divided into two doses (if necessary, the dose can be doubled);
-rheumatoid arthritis: up to 200 mg of the medicine twice a day;
-symptoms of ankylosing spondylitis: 200 mg of the medicament, single or divided into two doses;
-pain or menstruation pain: 400 mg at the beginning of treatment, followed by a lower dose to 200 mg twice a day.
In all cases, it should be taken regardless of food, without compromising the natural integrity of the capsules. Humans are better to know about features of application if there is prescription to buy cheap Celebrex online:
-patients of retirement age do not undergo dose adjustment;
-patients with mild forms of functional liver or kidney failure are not adjusted;
-during treatment, the risk of cardiovascular disorders should be taken into account, as a result of which the drug should be taken as soon as possible and at the lowest effective dosage;
-persons whose activities are related to the management of vehicles of various categories, the speed of response or the management of complex mechanisms, are recommended to abandon such work throughout the treatment.
The most common Celebrex side effects long term use are pain in the epigastric region, diarrhea, vomiting, nausea, possible development of intestinal bleeding, headache, drowsiness, dizziness, tinnitus, confusion, hypertension, arrhythmia, tachycardia, peripheral edema, infections of respiratory organs and genitourinary system, thrombocytopenia, anemia, allergic reactions. Celebrex weight gain is a rare adverse reaction using the preparation for a long time.
Symptoms and consequences of an overdose
Such medications like Mobic, Celebrex, Aleve pain killer, Pentagesic cannot be taken for longer than a week or in excessive dosages. If you exceed the dose or you treat for more than a week, then, most likely, you will come across side effects. If they appear, you need to rinse your stomach and go to the hospital.
Drug medication: what cannot be combined with Celebrex?
It is not recommended to take the above-described medication together with warfarin-based medications otherwise a negative effect can be provoked in the form of an increased likelihood of bleeding. Medications with Fluconazole and Ketoconazole in the composition increase the concentration of the active substance of this preparation in the blood twice. Therefore, you need to reduce the dosage or try not to combine these medications. In no case should you take several non-steroidal anti-inflammatory drugs at the same time, even if these medicines have different components.