Ultracet description and instructions for application

Ultracet is a combined anesthetic agent containing Tramadol and Acetaminophen. Is Ultracet a narcotic? It’s an opioid analgesic, which helps for severe and all natural pain relief. The substance Tramadol and its metabolites have the ability to activate so-called m-opiate receptors. Also, the compound activates non-opioid receptors through membrane hyperpolarization in spinal cord synapses and spinal neurons. It has the following effects on the brain and spinal cord: hyperpolarizes membranes and blocks pain impulses, helps to open sodium and calcium channels, strengthens the effects of soothing.


What is Ultracet?


Ultracet over the counter is taken in the case of:

-analgesia of painful therapeutic or diagnostic manipulations;

-posttraumatic, inflammatory or vascular pain syndrome (severe or moderate severity).

Instead of opioid painkiller doctor may prescribe Tylenol medication. It depends on the pain type.


Do not take Ultracet

Contraindications include:

-acute intoxication with alcohol or drugs depressing the central nervous system;

-taking concomitantly with MAO inhibitors or within 2 weeks after their withdrawal;

-severe hepatic or renal insufficiency;

-epilepsy, uncontrolled therapy; withdrawal syndrome;

-age up to 14 years; hypersensitivity to the components of the drug.

Ultracet during pregnancy is prohibited. Remedy is used with caution for shock, traumatic brain injury, increased intracranial pressure, propensity to convulsions. In therapeutically controlled epilepsy, the drug is prescribed only for vital indications. Also, with caution, the preparation is used for confusion of unknown origin, with respiratory failure, against the background of the use of psychotropic drugs and other analgesics of the central action, local anesthetics. Caution should be exercised in cases of bile duct disease, benign hyperbilirubinemia, viral hepatitis, deficiency of lucose-6-phosphate dehydrogenase, alcoholic liver damage, alcoholism, drug addiction, symptom-complex “acute” abdomen of unknown origin, in elderly patients (over 75 years old).


Instructions for use of Ultracet (method and dosage)


Ultracet dosage for back pain is taken orally, without chewing, with a small amount of water. You cannot double the next dose of the medicine if the patient forgot to take the pill on time. The starting single Ultracet dosage is 1-2 tablets. Patients should adhere to the interval between the use of tablets, which should be at least 6 hours. In patients aged (over 75 years), the interval between pills application is increased without changing the dosage. And in the case of violations in patients with kidney function (creatinine clearance from 10 to 30 ml / min), it should be at least 12 hours. If the patient is on chronic dialysis – after taking additional medication is not required, because Tramadol is almost not eliminated as a result of dialysis and hemofiltration. In the case of hepatic insufficiency, the interval of admission is increased, and with pronounced hepatic pathologies, they are not prescribed at all.


Ultracet side effects


The use of no prescription Ultracet can cause:

-Disorders of the central nervous system: general weakness, headache and dizziness, tremor, fatigue, spastic disorders, nervousness, anxiety, labile mood, euphoria, hallucinations. Also, when taking the product, confusion, insomnia or drowsiness, convulsive syndrome, depression, memory loss or loss, unstable gait, and taste and vision disturbances may occur.

-Allergic reactions: itching, rash, swelling.

-Gastrointestinal disorders: nausea, abdominal pain, vomiting, flatulence, dry mouth, diarrhea, difficulty swallowing, increased activity of hepatic transaminases.

-Disorders from the endocrine system: hypoglycemia, the formation of hypoglycemic coma.

-Violations of the cardiovascular system: orthostatic collapse, tachycardia, syncopal arrhythmia.

-Skin reactions: exanthema, erythema, Stephen-Johnson syndrome and Lyell, bullous rash.

-Disorders of the urinary system: difficulty urinating, dysuric phenomena, urinary retention. In the case of excess dosage and with unreasonably prolonged use, nephrotoxic effects such as interstitial nephritis or papillary necrosis are possible.

-Violations of hematopoiesis: aplastic anemia, pancytopenia, agranulocytosis.

-Other side effects: violation of the rhythm of breathing, excessive sweating, violation of the menstrual cycle. The decision on Ultracet appointment  and also other analgesics as generic Tylenol, Pentagesic, Ultram or Tramadol can only be taken by a doctor. Medicament is contraindicated in assigning to such categories of people as:

-patients with acute intoxication with psychotropic and hypnotic drugs, opioid analgesics, and also alcohol;

-patients with creatinine clearance less than 10 ml / min;

-children under 14 years;

-persons with “withdrawal syndrome”;

-patients who are hypersensitive to components;

-pregnant and lactating.


Can you overdose on Ultracet?


For acute Acetaminophen overdose (manifestations occur after 6-14 hours), a decrease in appetite and diarrhea are characteristic. In rare cases, liver or kidney failure may occur. Chronic overdose of Acetaminophen occurs, as a rule, after 2-4 days and is characterized by hypocoagulation, brain edema, arrhythmia, hypoglycemia, collapse. With an overdose of Tramadol, there are reactions such as miosis, vomiting, collapse, apnea, coma, convulsions, dyspnea, depression of the respiratory center.