Painkillers are widely used in modern life. Any of their representatives as Aceclofenac, Diclofenac tablet, Aleve, Celebrex, Panadol Extra, Cafergot must be found in the home medicine, any women’s handbag or in the car. Attacks of pain arise so suddenly that you will never know where this time it will overtake you. Therefore, often such medications are at hand, in which case do not run to the nearest pharmacy for help. People also use pain relief tape for injuries. One of the most effective painkillers today is Celebrex, which also has an anti-inflammatory effect. That is important for arthritis, pain in the joints, as well as other pain syndromes associated with inflammatory processes.
What is the medicinal preparation?
The main active component of such a medical preparation is Celecoxib, which possesses powerful analgesic properties and anti-inflammatory action. In addition, it also has antipyretic effect, which makes Celebrex over the counter quite popular drug in modern medicine. It refers to non-steroidal anti-inflammatory drugs, but complications associated with gastrointestinal diseases occur in it much less than other members of this extensive group. In addition, other studies were conducted, during which it was found that this medical product significantly reduces the risk of oncological diseases of the colon. The reception of such an anesthetic is shown as a symptomatic treatment under the following conditions: osteoarthritis, rheumatoid arthritis, and other types of arthritis; spondylitis; attacks of acute pain. American scientists have established that the popular cure for arthritis Celebrex for depression helps, enhancing the effect of antidepressants. Often, medicament is prescribed in complex therapy for the treatment of familial adenomatous polyposis, which results in a significant reduction in the size and quantity of colorectal adenomatous polyps. The method of administration, Celebrex dosage for back pain and duration of treatment with such a drug is usually prescribed by the attending physician, based on the diagnosis and severity of the disease, as well as on individual patient data.
Celebrex contraindications and negative reactions
It should be borne in mind that when buy Celebrex without prescription, the risks of thrombosis increase, so at the initial stages people should take this anti-inflammatory agent for some time in the lowest possible dosages. Explicit contraindications for the use of this non-steroidal anti-inflammatory drug are:
-hypersensitivity to any of the components included in its composition;
-postoperative period after coronary artery bypass grafting or other heart operations;
-allergy to any medical product of the NSAID group.
It is not recommended to take remedy during pregnancy, because there is a risk of developing pathologies in the fetus, as well as during breastfeeding, because of its ability to penetrate the mother’s milk. It is undesirable to use such a drug in childhood, with chronic heart failure and with a tendency to high blood pressure. The fact is that preparation can provoke a fluid retention, which will lead to the formation of peripheral edema, which is categorically undesirable for patients suffering from heart disease. Also in some cases, this medicine led to the development of hypertension, therefore, throughout the course of therapy, it is necessary to control blood pressure. The remedy can cause a nephrotoxic effect, so caution should be exercised in prescribing it to patients with impaired renal function. Does Celebrex cause weight gain? Weight gain is one of adverse reactions of medicine long-term application. Another reaction to taking the drug is a skin rash. In such cases, it is recommended to cancel therapy, as this can develop into Stevens-Johnson syndrome. Among other Celebrex side effects can be identified:
-dyspeptic disorders, flatulence, insomnia;
-rhinitis and cough, flu-like reactions and upper respiratory tract infections;
-peripheral puffiness, urinary tract infections;
-thrombocytopenia, anemia, increased anxiety, hearing impairment;
-arrhythmia and hypertension;
-allergic reactions: skin rash, burning, itching, angioedema;
-confusion, chronic heart failure;
-ulcerative formations in the digestive tract, inflammation of the pancreas.
At long receptions in the big doses the following phenomena can arise:
-ear infections, ulcerative lesions of the oral mucosa;
-stool disorder, hemorrhoidal and vaginal bleeding;
-disorders of the monthly cycle, symptoms of menopause;
-ischemic heart disease, myocardial infarction, angina pectoris, ventricular hypertrophy, arrhythmia;
-vein thrombosis and vascular arteriosclerosis;
-fungal infections, prostatitis;
Do humans that are indicated Celebrex abuse it? Generally medicament is not exposed to abuse. With an overdose of the drug, there is a significant increase in adverse reactions.
Interaction of Celebrex with alcoholic beverages
The interaction of Celebrex and alcohol leads to serious negative consequences. Moreover, its simultaneous use with ethanol is often fatal. It is known that alcohol has a harmful effect on the internal organs of the digestive system. Preparation also provokes the development of ulcerative diseases. That is, with their simultaneous use, the occurrence of various pathologies of the gastrointestinal tract increases several times. With this combination, often there are gastric bleeding, ulcers of the intestine and stomach. There is a risk of developing necrosis or cirrhosis of the liver, which leads to a fatal outcome. In addition, it should be borne in mind that Celebrex is excreted from the body with the help of the liver. And if it is at that time busy with ethanol processing, the concentration of the drug in the body will increase significantly, which will undoubtedly lead to an overdose and the consequences associated with it. This medication is not recommended for patients who underwent heart surgery, as well as having a history of chronic heart failure. The destructive effect of alcohol-containing substances on cardiovascular activity is known to almost everyone. Also many other drugs, especially analgesics such as Diclofenac generic, are not allowed to be combined with alcohol.